An intramolecular inverse electron demand Diels–Alder approach to annulated α-carbolines

An intramolecular inverse electron demand Diels–Alder approach to annulated α-carbolines

Intramolecular inverse electron demand cycloadditions of isatin-derived 1,2,4-triazines with acetylenic dienophiles tethered by amidations or transesterifications proceed in excellent yields to produce lactam- or lactone-fused α-carbolines. Beginning with various isatins and alkynyl dienophiles, a p...

Full description

Bibliographic Details
Main Authors: Zhiyuan Ma, Feng Ni, Grace H. C. Woo, Sie-Mun Lo, Philip M. Roveto, Scott E. Schaus, John K. Snyder
Format: Article
Language:English
Published: Beilstein-Institut 2012-06-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
α-carboline
chemical diversity
inverse electron demand Diels–Alder
isatin
pyrido[2,3-b]indole
1,2,4-triazine
Online Access:https://doi.org/10.3762/bjoc.8.93

Internet

https://doi.org/10.3762/bjoc.8.93

Similar Items