Effect of Hydroxytyrosol Derivatives of Donepezil on the Activity of Enzymes Involved in Neurodegenerative Diseases and Oxidative Damage

Effect of Hydroxytyrosol Derivatives of Donepezil on the Activity of Enzymes Involved in Neurodegenerative Diseases and Oxidative Damage

Monoamine oxidase and xanthine oxidase inhibitors represent useful multi-target drugs for the prevention, attenuation, and treatment of oxidative damage and neurodegenerative disorders. Chimeric molecules, constituted by naturally derived compounds linked to drugs, represent lead compounds to be exp...

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Bibliographic Details
Main Authors: Antonio D’Errico, Rosarita Nasso, Rosario Rullo, Jessica Maiuolo, Paola Costanzo, Sonia Bonacci, Manuela Oliverio, Emmanuele De Vendittis, Mariorosario Masullo, Rosaria Arcone
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molecules
Subjects:
hydroxytyrosol-donepezil hybrid
inflammatory diseases
neurodegenerative disorders
monoamine oxidase (MAO)
xanthine oxidase (XO)
multitargeting agents
Online Access:https://www.mdpi.com/1420-3049/29/2/548

Internet

https://www.mdpi.com/1420-3049/29/2/548

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