Causal association between constipation and risk of colorectal cancer: a bidirectional two-sample Mendelian randomization study

BackgroundColorectal cancer (CRC) is a globally significant health concern, necessitating effective preventive strategies through identifying modifiable risk factors. Constipation, characterized by infrequent bowel movements or difficulty passing stools, has been proposed as a potential CRC risk fac...

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Bibliographic Details
Main Authors: Long Wu, Huan Wu, Fei Huang, Xiao-yun Li, Yun-huan Zhen, Bao-fang Zhang, Hai-yang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1282066/full