Data-driven asthma endotypes defined from blood biomarker and gene expression data.

The diagnosis and treatment of childhood asthma is complicated by its mechanistically distinct subtypes (endotypes) driven by genetic susceptibility and modulating environmental factors. Clinical biomarkers and blood gene expression were collected from a stratified, cross-sectional study of asthmati...

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Bibliographic Details
Main Authors: Barbara Jane George, David M Reif, Jane E Gallagher, ClarLynda R Williams-DeVane, Brooke L Heidenfelder, Edward E Hudgens, Wendell Jones, Lucas Neas, Elaine A Cohen Hubal, Stephen W Edwards
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4314082?pdf=render