Generation of human iPSC-derived neurofibromaspheres for in vitro and in vivo uses

Generation of human iPSC-derived neurofibromaspheres for in vitro and in vivo uses

Summary: Neurofibromas are benign peripheral nervous system tumors associated with neurofibromatosis type 1, which originate from NF1(−/−) Schwann cell precursors. We describe a protocol to generate neurofibromaspheres by differentiating NF1(−/−) Schwann cells from induced pluripotent stem cells and...

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Bibliographic Details
Main Authors: Helena Mazuelas, Itziar Uriarte-Arrazola, Juana Fernández-Rodríguez, Miriam Magallón-Lorenz, Alberto Villanueva, Conxi Lázaro, Bernat Gel, Eduard Serra, Meritxell Carrió
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:STAR Protocols
Subjects:
Cell Biology
Cancer
Model Organisms
Cell Differentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166723001569

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http://www.sciencedirect.com/science/article/pii/S2666166723001569

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