Structure, kinetic characterization and subcellular localization of the two ribulose 5-phosphate epimerase isoenzymes from Trypanosoma cruzi.

The enzyme of the pentose phosphate pathway (PPP) ribulose-5-phosphate-epimerase (RPE) is encoded by two genes present in the genome of Trypanosoma cruzi CL Brener clone: TcRPE1 and TcRPE2. Despite high sequence similarity at the amino acid residue level, the recombinant isoenzymes show a strikingly...

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Détails bibliographiques
Auteurs principaux: Soledad Natalia Gonzalez, Wanda Mariela Valsecchi, Dante Maugeri, José María Delfino, Juan José Cazzulo
Format: Article
Langue:English
Publié: Public Library of Science (PLoS) 2017-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC5312968?pdf=render