Influenza M2 virus-like particle vaccination enhances protection in combination with avian influenza HA VLPs.

Despite the ability to induce a broad range of cross protection, M2e5x virus-like particles (VLPs) alone provide limited vaccine efficacy and confer low efficacy of protection against highly pathogenic avian influenza virus (HPAIV) infection in chickens. Avian influenza hemagglutinin (HA) has been a...

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Bibliographic Details
Main Authors: Hae-Ji Kang, Ki-Back Chu, Dong-Hun Lee, Su-Hwa Lee, Bo Ryoung Park, Min-Chul Kim, Sang-Moo Kang, Fu-Shi Quan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0216871