Amino Acid Biosynthesis Regulation during Endoplasmic Reticulum Stress Is Coupled to Protein Expression Demands
Summary: The endoplasmic reticulum (ER) stress response, also known as the unfolded protein response (UPR), is a complex cellular response to ER protein misfolding that involves transcriptional regulatory branches and a PERK-mediated translational regulatory branch.Here we revealed that amino acid b...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-09-01
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Series: | iScience |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004219302470 |