The role of ERBB2 gene polymorphisms in leprosy susceptibility
Mycobacterium leprae infects skin and peripheral nerves causing deformities and disability. The M. leprae bacterium binds to ErbB2 on the Schwann cell surface causing demyelination and favoring spread of the bacilli and causing nerve injury. Polymorphisms at the ERBB2 gene were previously investigat...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-03-01
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Series: | Brazilian Journal of Infectious Diseases |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1413867015000306 |