The role of ERBB2 gene polymorphisms in leprosy susceptibility

Mycobacterium leprae infects skin and peripheral nerves causing deformities and disability. The M. leprae bacterium binds to ErbB2 on the Schwann cell surface causing demyelination and favoring spread of the bacilli and causing nerve injury. Polymorphisms at the ERBB2 gene were previously investigat...

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Bibliographic Details
Main Authors: Jamile Leão Rêgo, Joyce Moura Oliveira, Nadja de Lima Santana, Paulo Roberto Lima Machado, Léa Cristina Castellucci
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Brazilian Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1413867015000306