Neutrophil Extracellular Traps Induce the Epithelial-Mesenchymal Transition: Implications in Post-COVID-19 Fibrosis

Neutrophil Extracellular Traps Induce the Epithelial-Mesenchymal Transition: Implications in Post-COVID-19 Fibrosis

The release of neutrophil extracellular traps (NETs), a process termed NETosis, avoids pathogen spread but may cause tissue injury. NETs have been found in severe COVID-19 patients, but their role in disease development is still unknown. The aim of this study is to assess the capacity of NETs to dri...

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Bibliographic Details
Main Authors: Laura Pandolfi, Sara Bozzini, Vanessa Frangipane, Elena Percivalle, Ada De Luigi, Martina Bruna Violatto, Gianluca Lopez, Elisa Gabanti, Luca Carsana, Maura D’Amato, Monica Morosini, Mara De Amici, Manuela Nebuloni, Tommaso Fossali, Riccardo Colombo, Laura Saracino, Veronica Codullo, Massimiliano Gnecchi, Paolo Bigini, Fausto Baldanti, Daniele Lilleri, Federica Meloni
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
NETosis
SARS-CoV2
COVID-19
epithelial-mesenchymal transition
lung fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.663303/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.663303/full

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