Pantothenate biosynthesis in Toxoplasma gondii tachyzoites is not a drug target

Pantothenate biosynthesis in Toxoplasma gondii tachyzoites is not a drug target

Toxoplasma gondii is a pervasive apicomplexan parasite that can cause severe disease and death in immunocompromised individuals and the developing foetus. The treatment of toxoplasmosis often leads to serious side effects and novel drugs and drug targets are therefore actively sought. In 2014, Magee...

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Bibliographic Details
Main Authors: Vanessa M. Howieson, Joy Zeng, Joachim Kloehn, Christina Spry, Chiara Marchetti, Matteo Lunghi, Emmanuel Varesio, Andrew Soper, Anthony G. Coyne, Chris Abell, Giel G. van Dooren, Kevin J. Saliba
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Pantothenate synthetase
Pantoate β-alanine ligase
T. gondii
SW314
Pantothenate
PanC
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320723000118

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http://www.sciencedirect.com/science/article/pii/S2211320723000118

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