Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
Abstract Tissue patterning is critical for the development and regeneration of organs. To advance the use of engineered reconstituted skin organs, we study cardinal features important for tissue patterning and hair regeneration. We find they spontaneously form spheroid configurations, with polarized...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-11-01
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Series: | npj Regenerative Medicine |
Online Access: | https://doi.org/10.1038/s41536-023-00340-0 |