Newcastle Disease Virus Induces Profound Lymphoid Depletion with Different Patterns of Necroptosis, Necrosis, and Oxidative DNA Damage in Bursa, Spleen, and Other Lymphoid Tissues

Newcastle Disease Virus Induces Profound Lymphoid Depletion with Different Patterns of Necroptosis, Necrosis, and Oxidative DNA Damage in Bursa, Spleen, and Other Lymphoid Tissues

This study delves into the pathogenesis of virulent genotype VII strains of the Newcastle disease virus (NDV), focusing on experimentally infected birds. Predominant and consistent lesions observed include bursal atrophy and extensive depletion of all lymphoid tissues. Immunohistochemistry (IHC) ana...

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Detalles Bibliográficos
Autores principales: Mohammad Rabiei, Milton M. McAllister, Natalie R. Gassman, Kevin J. Lee, Sydney Acton, Dieter Liebhart, Wai Yee Low, Farhid Hemmatzadeh
Formato: Artículo
Lenguaje:English
Publicado: MDPI AG 2024-07-01
Colección:Pathogens
Materias:
Newcastle disease virus (NDV)
lymphoid depletion
necroptosis
apoptosis
repair assisted damage detection (RADD)
oxidative damage
Acceso en línea:https://www.mdpi.com/2076-0817/13/8/619

Internet

https://www.mdpi.com/2076-0817/13/8/619

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