Effects of odanacatib on bone matrix mineralization in rhesus monkeys are similar to those of alendronate

Odanacatib (ODN) is a selective and reversible inhibitor of cathepsin K which is an important enzyme for the degradation of collagen I. Aim of the present work was the head-to-head comparison between the effects of ODN and alendronate (ALN) on bone mineralization density distribution (BMDD), based o...

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Bibliographic Details
Main Authors: Barbara M. Misof, Paul Roschger, Charles Chen, Maureen Pickarski, Phaedra Messmer, Klaus Klaushofer, Le T. Duong
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Bone Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187216300109