Binding interactions of epididymal protease inhibitor and semenogelin-1: a homology modeling, docking and molecular dynamics simulation study
Epididymal protease inhibitor (EPPIN) that is located on the sperm surface and specific to the male reproductive system is a non-hormonal contraceptive target, since the binding of EPPIN with the seminal plasma protein semenogelin-1 (SEMG1) causes a loss of sperm function. Here, we investigated the...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2019-08-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/7329.pdf |