ALDH1A2 (RALDH2) genetic variation in human congenital heart disease

ALDH1A2 (RALDH2) genetic variation in human congenital heart disease

<p>Abstract</p> <p>Background</p> <p>Signaling by the vitamin A-derived morphogen retinoic acid (RA) is required at multiple steps of cardiac development. Since conversion of retinaldehyde to RA by retinaldehyde dehydrogenase type II (ALDH1A2, a.k.a RALDH2) is critical...

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Main Authors: Mesquita Sonia MF, Marques Lívia P, Vasconcelos Michelle, Cravo Roberta M, Sobreira Tiago J, Silva Fábio A, Ruiz Viviane F, Pavan Marilene, Krieger José E, Lopes Antônio AB, Oliveira Paulo S, Pereira Alexandre C, Xavier-Neto José
Format: Article
Language:English
Published: BMC 2009-11-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/10/113

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http://www.biomedcentral.com/1471-2350/10/113

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