Metabolomics data normalization with EigenMS.

Liquid chromatography mass spectrometry has become one of the analytical platforms of choice for metabolomics studies. However, LC-MS metabolomics data can suffer from the effects of various systematic biases. These include batch effects, day-to-day variations in instrument performance, signal inten...

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Bibliographic Details
Main Authors: Yuliya V Karpievitch, Sonja B Nikolic, Richard Wilson, James E Sharman, Lindsay M Edwards
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4280143?pdf=render