Circulating TFH subset distribution is strongly affected in lupus patients with an active disease.

Follicular helper T cells (TFH) represent a distinct subset of CD4(+) T cells specialized in providing help to B lymphocytes, which may play a central role in autoimmune diseases having a major B cell component such as systemic lupus erythematosus. Recently, TFH subsets that share common phenotypic...

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Bibliographic Details
Main Authors: Carole Le Coz, Aurélie Joublin, Jean-Louis Pasquali, Anne-Sophie Korganow, Hélène Dumortier, Fanny Monneaux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3777901?pdf=render