Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system

Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system

Abstract Chemokine receptors constitute an important subfamily of G protein-coupled receptors (GPCRs), and they are critically involved in a broad range of immune response mechanisms. Ligand promiscuity among these receptors makes them an interesting target to explore multiple aspects of biased agon...

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Detalhes bibliográficos
Main Authors: Parishmita Sarma, Carlo Marion C. Carino, Deeksha Seetharama, Shubhi Pandey, Hemlata Dwivedi-Agnihotri, Xue Rui, Yubo Cao, Kouki Kawakami, Poonam Kumari, Yu-Chih Chen, Kathryn E. Luker, Prem N. Yadav, Gary D. Luker, Stéphane A. Laporte, Xin Chen, Asuka Inoue, Arun K. Shukla
Formato: Artigo
Idioma:English
Publicado em: Nature Portfolio 2023-08-01
Colecção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-023-40482-9

Internet

https://doi.org/10.1038/s41467-023-40482-9

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