Limited expression of Nrf2 in neurons across the central nervous system
Nrf2, encoded by the gene Nfe2l2, is a broadly expressed transcription factor that regulates gene expression in response to reactive oxygen species (ROS) and oxidative stress. It is commonly referred to as a ubiquitous pathway, but this generalization overlooks work indicating that Nrf2 is essential...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-09-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231723002318 |