Limited expression of Nrf2 in neurons across the central nervous system

Nrf2, encoded by the gene Nfe2l2, is a broadly expressed transcription factor that regulates gene expression in response to reactive oxygen species (ROS) and oxidative stress. It is commonly referred to as a ubiquitous pathway, but this generalization overlooks work indicating that Nrf2 is essential...

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Bibliographic Details
Main Authors: Daniel C. Levings, Salil Saurav Pathak, Yi-Mei Yang, Matthew Slattery
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723002318