Functional characterization of a chimeric lipase genetically engineered from human lipoprotein lipase and human hepatic lipase

Functional characterization of a chimeric lipase genetically engineered from human lipoprotein lipase and human hepatic lipase

Lipoprotein lipase (LPL) and hepatic lipase (HL) mediate the hydrolysis of triglycerides and phospholipids present in circulating lipoprotein particles and are essential for normal lipid metabolism. Both enzymes have a similar primary amino acid structure and share requirements for intact catalytic,...

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Bibliographic Details
Main Authors: HL Dichek, C Parrott, R Ronan, JD Brunzell, HB Brewer, Jr, S Santamarina-Fojo
Format: Article
Language:English
Published: Elsevier 1993-08-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520369686

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http://www.sciencedirect.com/science/article/pii/S0022227520369686

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