A regression approach for assessing large molecular drug concentration in breast milk

A regression approach for assessing large molecular drug concentration in breast milk

The development of an effective method for predicting the transfer of biologics from plasma into breast milk is important to ensure the safe use of medications during lactation. The aim of this study was to develop a regression model that could predict the transfer of monoclonal antibodies (mAbs) an...

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Bibliographic Details
Main Authors: Allesandra Stratigakis, Dylan Paty, Peng Zou, Zhongyuan Zhao, Yanyan Li, Tao Zhang
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2023-12-01
Series:Reproduction and Breeding
Subjects:
Regression model
Milk to plasma concentration ratio (M/P)
Large molecule drugs
Breast milk
Lactation
Pharmacokinetics
Online Access:http://www.sciencedirect.com/science/article/pii/S266707122300042X

Internet

http://www.sciencedirect.com/science/article/pii/S266707122300042X

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