Effects of DA-9801 on the inflammation and apoptosis induced by angiotensin II in human dermal microvascular endothelial cells

Effects of DA-9801 on the inflammation and apoptosis induced by angiotensin II in human dermal microvascular endothelial cells

DA-9801, a plant-based drug used for the treatment of diabetic neuropathy, is known to improve angiotensin II (Ang II)-induced vascular endothelial cell dysfunction. However, the underlying mechanism is not fully understood. We aimed to determine whether the protective effect of DA-9801 against Ang...

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Bibliographic Details
Main Authors: Oak-Kee Hong, Seong-Su Lee, Soon Jib Yoo, Song-Hyen Choi, Min-Kyung Lee, Bong-Yun Cha, Mee-Kyoung Kim, Ki-Hyun Baek, Ki-Ho Song, Hyuk-Sang Kwon
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of Pharmacological Sciences
Subjects:
Angiotensin II
Dermal microvascular endothelial cells
DA-9801
Apoptosis
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861320301067

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http://www.sciencedirect.com/science/article/pii/S1347861320301067

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