Regioselective Synthesis of 4-Bromo-3-formyl-<i>N</i>-phenyl-5-propylthiophene-2-carboxamide
We synthesized 4-bromo-3-formyl-<i>N</i>-phenyl-5-propylthiophene-2-carboxamide by using three successive direct lithiations and a bromination reaction starting from thiophene. All these lithiation reactions were carried out at −78 °C to RT over a period of 1 to 24 h based on the reactiv...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-11-01
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| Series: | Molbank |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-8599/2021/4/M1296 |