Prostaglandin E2/Leukotriene B4 balance induced by Lutzomyia longipalpis saliva favors Leishmania infantum infection

Prostaglandin E2/Leukotriene B4 balance induced by Lutzomyia longipalpis saliva favors Leishmania infantum infection

Abstract Background Eicosanoids and sand fly saliva have a critical role in the Leishmania infection. Here, we evaluated the effect of Lutzomyia longipalpis salivary gland sonicate (SGS) on neutrophil and monocyte recruitment and activation of eicosanoid production in a murine model of inflammation....

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Bibliographic Details
Main Authors: Théo Araújo-Santos, Deboraci Brito Prates, Jaqueline França-Costa, Nívea F Luz, Bruno B Andrade, José Carlos Miranda, Claudia I Brodskyn, Aldina Barral, Patrícia T Bozza, Valéria Matos Borges
Format: Article
Language:English
Published: BMC 2014-12-01
Series:Parasites & Vectors
Subjects:
Lutzomyia longipalpis
Leishmania infantum
Saliva
Prostaglandina E2
Leukotriene B4
Online Access:https://doi.org/10.1186/s13071-014-0601-8

Internet

https://doi.org/10.1186/s13071-014-0601-8

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