Notch ankyrin domain: evolutionary rise of a thermodynamic sensor
Abstract Notch signalling pathway plays a key role in metazoan biology by contributing to resolution of binary decisions in the life cycle of cells during development. Outcomes such as proliferation/differentiation dichotomy are resolved by transcriptional remodelling that follows a switch from Notc...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-05-01
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Series: | Cell Communication and Signaling |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12964-022-00886-4 |