Pazopanib restricts small cell lung cancer proliferation via reactive oxygen species‐mediated endoplasmic reticulum stress

Pazopanib restricts small cell lung cancer proliferation via reactive oxygen species‐mediated endoplasmic reticulum stress

Abstract Background Pazopanib is an approved multitarget anticancer agent for soft tissue sarcoma (STS) and renal cell carcinoma (RCC), which is also under clinical investigation for other malignancies, including small cell lung cancer (SCLC). However, the potential anti‐SCLC mechanisms of pazopanib...

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Bibliographic Details
Main Authors: Yue Li, Chen Chen, Hai‐Lin Liu, Chen‐Guang Li, Zhen‐Fa Zhang, Chang‐Li Wang
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Thoracic Cancer
Subjects:
apoptosis
endoplasmic reticulum stress (ER‐stress)
Pazopanib
reactive oxygen species (ROS)
small cell lung cancer (SCLC)
Online Access:https://doi.org/10.1111/1759-7714.14543

Internet

https://doi.org/10.1111/1759-7714.14543

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