R-Ras GTPases Signaling Role in Myelin Neurodegenerative Diseases

R-Ras GTPases Signaling Role in Myelin Neurodegenerative Diseases

Myelination is required for fast and efficient synaptic transmission in vertebrates. In the central nervous system, oligodendrocytes are responsible for creating myelin sheaths that isolate and protect axons, even throughout adulthood. However, when myelin is lost, the failure of remyelination mecha...

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Bibliographic Details
Main Authors: Berta Alcover-Sanchez, Gonzalo Garcia-Martin, Francisco Wandosell, Beatriz Cubelos
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
myelin
oligodendrocyte
neurodegeneration
PI3K/Akt/mTOR
ERK1/2-MAPK
Wnt/β-catenin
Online Access:https://www.mdpi.com/1422-0067/21/16/5911

Internet

https://www.mdpi.com/1422-0067/21/16/5911

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