Addition of bone morphogenetic protein type 2 to ascorbate and β-glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells

Addition of bone morphogenetic protein type 2 to ascorbate and β-glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells

Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells. OBJECTIVES: This study evaluated the effect of a recombinant BMP-2 as well as the endogenous BMP-4 and BMP-7 in the osteogenic d...

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Bibliographic Details
Main Authors: Ariadne Cristiane Cabral Cruz, Mariana Lúcia Silva, Thiago Caon, Cláudia Maria Oliveira Simões
Format: Article
Language:English
Published: University of São Paulo 2012-12-01
Series:Journal of Applied Oral Science
Subjects:
Stem cells
Cell differentiation
Osteogenesis
Bone morphogenetic protein 2
Bone morphogenetic protein 4
Bone morphogenetic protein 7
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572012000600007

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572012000600007

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