HAlign-II: efficient ultra-large multiple sequence alignment and phylogenetic tree reconstruction with distributed and parallel computing

HAlign-II: efficient ultra-large multiple sequence alignment and phylogenetic tree reconstruction with distributed and parallel computing

Abstract Background Multiple sequence alignment (MSA) plays a key role in biological sequence analyses, especially in phylogenetic tree construction. Extreme increase in next-generation sequencing results in shortage of efficient ultra-large biological sequence alignment approaches for coping with d...

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Bibliographic Details
Main Authors: Shixiang Wan, Quan Zou
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Algorithms for Molecular Biology
Subjects:
Multiple sequence alignment
Phylogenetic trees
Distributed computing
Spark
Online Access:http://link.springer.com/article/10.1186/s13015-017-0116-x

Internet

http://link.springer.com/article/10.1186/s13015-017-0116-x

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