PoRVA G9P[23] and G5P[7] infections differentially promote PEDV replication by reprogramming glutamine metabolism.

PoRVA and PEDV coinfections are extremely common in clinical practice. Although coinfections of PoRVA and PEDV are known to result in increased mortality, the underlying mechanism remains unknown. Here, we found that PoRVA infection promoted PEDV infection in vivo and in vitro and that PoRVA G9P[23]...

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Bibliographic Details
Main Authors: Haixin Liu, Haolun Tian, Pengcheng Hao, Huimin Du, Kun Wang, Yudong Qiu, Xiangrui Yin, Nana Wu, Qian Du, Dewen Tong, Yong Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012305