Inflammatory Bone Marrow Mesenchymal Stem Cells in Multiple Myeloma: Transcriptional Signature and In Vitro Modeling

Inflammatory Bone Marrow Mesenchymal Stem Cells in Multiple Myeloma: Transcriptional Signature and In Vitro Modeling

Bone marrow mesenchymal stem cells (BM MSCs) play a tumor-supportive role in promoting drug resistance and disease relapse in multiple myeloma (MM). Recent studies have discovered a sub-population of MSCs, known as inflammatory MSCs (iMSCs), exclusive to the MM BM microenvironment and implicated in...

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Bibliographic Details
Main Authors: Lei Wang, Weijun Yi, Li Ma, Emily Lecea, Lori A. Hazlehurst, Donald A. Adjeroh, Gangqing Hu
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
multiple myeloma
bone marrow
inflammatory MSCs
transcriptional signature
IL-1β
Online Access:https://www.mdpi.com/2072-6694/15/21/5148

Internet

https://www.mdpi.com/2072-6694/15/21/5148

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