Linking profiles of pathway activation with clinical motor improvements – A retrospective computational study

Linking profiles of pathway activation with clinical motor improvements – A retrospective computational study

Background: Deep brain stimulation (DBS) is an established therapy for patients with Parkinson’s disease. In silico computer models for DBS hold the potential to inform a selection of stimulation parameters. In recent years, the focus has shifted towards DBS-induced firing in myelinated axons, deeme...

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Bibliographic Details
Main Authors: Konstantin Butenko, Ningfei Li, Clemens Neudorfer, Jan Roediger, Andreas Horn, Gregor R. Wenzel, Hazem Eldebakey, Andrea A. Kühn, Martin M. Reich, Jens Volkmann, Ursula van Rienen
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:NeuroImage: Clinical
Subjects:
Deep brain stimulation
Pathway activation
UPDRS-III score
Pallidothalamic pathway
Computational modeling
Parkinson’s disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158222002509

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http://www.sciencedirect.com/science/article/pii/S2213158222002509

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