Case report: Cerebrospinal fluid-derived circulating tumor DNA diagnoses and guides the treatment of a lung adenocarcinoma case with leptomeningeal metastasis

Case report: Cerebrospinal fluid-derived circulating tumor DNA diagnoses and guides the treatment of a lung adenocarcinoma case with leptomeningeal metastasis

Leptomeningeal metastasis (LM) occurs in 3~5% of non-small cell lung cancer (NSCLC) patients. Diagnosis of patients with LM and disease monitoring remains challenging due to the low sensitivity and specificity of the commonly used approaches, such as cerebrospinal fluid (CSF) cytology and magnetic r...

Full description

Bibliographic Details
Main Authors: Yujun Bai, Qingxi Yu, Ning Liu, Jingwen Liu, Di Wang, Xiaoli Liu, Shuanghu Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
NSCLC
ctDNA
leptomeningeal metastasis (LM)
cerebrospinal fluid (CSF)
case report
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.944963/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.944963/full

Similar Items