The In Vitro and In Vivo Anticancer Properties of Chalcone Flavokawain B through Induction of ROS-Mediated Apoptotic and Autophagic Cell Death in Human Melanoma Cells

The In Vitro and In Vivo Anticancer Properties of Chalcone Flavokawain B through Induction of ROS-Mediated Apoptotic and Autophagic Cell Death in Human Melanoma Cells

Melanoma is the most prevalent type of skin cancer with high mortality rates. This study demonstrates the in vitro and in vivo anticancer properties of chalcone flavokawain B (FKB) induced ROS-mediated apoptosis and autophagy in human melanoma (human epithelial melanoma cell line A375 and/or human s...

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Bibliographic Details
Main Authors: You-Cheng Hseu, Yu-Chi Chiang, Yugandhar Vudhya Gowrisankar, Kai-Yuan Lin, Sheng-Teng Huang, Sirjana Shrestha, Geng-Ruei Chang, Hsin-Ling Yang
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
flavokawain B
melanoma cells
apoptosis
autophagy
ROS
Online Access:https://www.mdpi.com/2072-6694/12/10/2936

Internet

https://www.mdpi.com/2072-6694/12/10/2936

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