Identification of Novel Subcellular Localization and Trafficking of HIV-1 Nef Variants from Reference Strains G (F1.93.HH8793) and H (BE.93.VI997)

The human immunodeficiency virus type 1 (HIV-1) accessory protein Nef, plays an essential role in disease progression and pathogenesis via hijacking the host cellular membrane-trafficking machinery. Interestingly, HIV-1 group-M subtypes display differences in the rate of disease progression. However...

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Bibliographic Details
Main Authors: Logan R. Van Nynatten, Aaron L. Johnson, Brennan S. Dirk, Emily N. Pawlak, Rajesh Abraham Jacob, S. M. Mansour Haeryfar, Jimmy D. Dikeakos
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/10/9/493