Natural history of a mouse model of X-linked myotubular myopathy

Natural history of a mouse model of X-linked myotubular myopathy

X-linked myotubular myopathy (XLMTM) is a severe monogenetic disorder of the skeletal muscle. It is caused by loss-of-expression/function mutations in the myotubularin (MTM1) gene. Much of what is known about the disease, as well as the treatment strategies, has been uncovered through experimentatio...

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Bibliographic Details
Main Authors: Ege Sarikaya, Nesrin Sabha, Jonathan Volpatti, Emanuela Pannia, Nika Maani, Hernan D. Gonorazky, Alper Celik, Yijng Liang, Paula Onofre-Oliveira, James J. Dowling
Format: Article
Language:English
Published: The Company of Biologists 2022-07-01
Series:Disease Models & Mechanisms
Subjects:
mice
myotubularin
myotubular myopathy
muscle disease
natural history
Online Access:http://dmm.biologists.org/content/15/7/dmm049342

Internet

http://dmm.biologists.org/content/15/7/dmm049342

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