Extra Loading Dose of Dexmedetomidine Enhances Intestinal Function Recovery After Colorectal Resection: A Retrospective Cohort Study

Extra Loading Dose of Dexmedetomidine Enhances Intestinal Function Recovery After Colorectal Resection: A Retrospective Cohort Study

Importance: Postoperative gastrointestinal dysfunction (POGD) may be caused by postoperative vagus nerve tension inhibition and systemic inflammation. Dexmedetomidine (Dex) increases vagus nerve tone and affords an anti-inflammatory property, which may play a role in pathogenesis.Objective: To inves...

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Bibliographic Details
Main Authors: Guo-Zun He, Ning Bu, Ya-Juan Li, Yuan Gao, Ge Wang, Zhi-Dong Kong, Min Zhao, Shan-Shan Zhang, Wei Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
postsurgical recovery
dexmedetomidine
colorectal tumor
systemic inflammation
postoperative gastrointestinal dysfunction
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.806950/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.806950/full

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