LncRNA OIP5-AS1 Promotes the Autophagy-Related Imatinib Resistance in Chronic Myeloid Leukemia Cells by Regulating miR-30e-5p/ATG12 Axis

LncRNA OIP5-AS1 Promotes the Autophagy-Related Imatinib Resistance in Chronic Myeloid Leukemia Cells by Regulating miR-30e-5p/ATG12 Axis

Background: Resistance to tyrosine kinase inhibitors (TKIs) in patients with chronic myeloid leukemia (CML) remains a problem in clinical treatment, and the mechanism has not been fully clarified. Autophagy can protect cancer cells under chemotherapeutic stimulation. Long noncoding RNAs (lncRNAs) ar...

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Bibliographic Details
Main Authors: Hongdan Dai MS, Jianming Wang MS, Zhenglan Huang PhD, Hui Zhang PhD, Xin Wang PhD, Qian Li PhD, Wenli Feng MD
Format: Article
Language:English
Published: SAGE Publishing 2021-10-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/15330338211052150

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https://doi.org/10.1177/15330338211052150

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