Reciprocal Inhibition of Immunogenic Performance in Mice of Two Potent DNA Immunogens Targeting HCV-Related Liver Cancer

Reciprocal Inhibition of Immunogenic Performance in Mice of Two Potent DNA Immunogens Targeting HCV-Related Liver Cancer

Chronic HCV infection and associated liver cancer impose a heavy burden on the healthcare system. Direct acting antivirals eliminate HCV, unless it is drug resistant, and partially reverse liver disease, but they cannot cure HCV-related cancer. A possible remedy could be a multi-component immunother...

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Bibliographic Details
Main Authors: Juris Jansons, Dace Skrastina, Alisa Kurlanda, Stefan Petkov, Darya Avdoshina, Yulia Kuzmenko, Olga Krotova, Olga Trofimova, Ilya Gordeychuk, Irina Sominskaya, Maria Isaguliants
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Microorganisms
Subjects:
hepatitis C virus
hepatocellular carcinoma
immunotherapy
multi-component DNA vaccine
nucleocapsid (core) protein
telomerase reverse transcriptase
Online Access:https://www.mdpi.com/2076-2607/9/5/1073

Internet

https://www.mdpi.com/2076-2607/9/5/1073

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