Development of iRGD-Modified Peptide Carriers for Suicide Gene Therapy of Uterine Leiomyoma

Development of iRGD-Modified Peptide Carriers for Suicide Gene Therapy of Uterine Leiomyoma

Uterine leiomyoma (UL) is one of the most common benign tumors in women that often leads to many reproductive complications. Suicide genetherapy was suggested as a promising approach for UL treatment. In the present study, we describe iRGD ligand-conjugated cysteine-rich peptide carrier RGD1-R6 for...

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Bibliographic Details
Main Authors: Anna Egorova, Sofia Shtykalova, Alexander Selutin, Natalia Shved, Marianna Maretina, Sergei Selkov, Vladislav Baranov, Anton Kiselev
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Pharmaceutics
Subjects:
DNA delivery
peptide-based carriers
gene therapy
thymidine kinase
uterine leiomyoma
integrins
Online Access:https://www.mdpi.com/1999-4923/13/2/202

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https://www.mdpi.com/1999-4923/13/2/202

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