Exosomes from Human Placenta Choriodecidual Membrane-Derived Mesenchymal Stem Cells Mitigate Endoplasmic Reticulum Stress, Inflammation, and Lung Injury in Lipopolysaccharide-Treated Obese Mice

Exosomes from Human Placenta Choriodecidual Membrane-Derived Mesenchymal Stem Cells Mitigate Endoplasmic Reticulum Stress, Inflammation, and Lung Injury in Lipopolysaccharide-Treated Obese Mice

Endoplasmic reticulum (ER) stress mediates the effects of obesity on aggravating sepsis-induced lung injury. We investigated whether exosomes from human placenta choriodecidual membrane-derived mesenchymal stem cells (pcMSCs) can mitigate pulmonary ER stress, lung injury, and the mechanisms of infla...

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Bibliographic Details
Main Authors: Milton D. Chiang, Chao-Yuan Chang, Hung-Jen Shih, Van Long Le, Yen-Hua Huang, Chun-Jen Huang
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Antioxidants
Subjects:
lung injury
obesity
endoplasmic reticulum stress
exosomes
LPS
Online Access:https://www.mdpi.com/2076-3921/11/4/615

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https://www.mdpi.com/2076-3921/11/4/615

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