Protective effect of α7 nicotinic acetylcholine receptor activation on experimental colitis and its mechanism

Abstract Background Inflammatory bowel disease (IBD) is a common chronic remitting disease with no satisfactory treatment. The aim of this study was to investigate the protective effect of α7 nicotinic acetylcholine receptor (α7nAChR), and to determine the underlying mechanism of its activity. Metho...

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Bibliographic Details
Main Authors: Wenyuan Pu, Zhenzi Su, Junaid Wazir, Chen Zhao, Lulu Wei, Ranran Wang, Qiyi Chen, Saifang Zheng, Shaoyi Zhang, Hongwei Wang
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-022-00532-2