The Construction of Cucurbit[7]uril-Based Supramolecular Nanomedicine for Glioma Therapy

Two supramolecular nanomedicines (CB[7]⊃DOX and CB[7]⊃CPT) based on the host–guest recognition between CB[7] and anticancer drugs were constructed. After supramolecular modification, the stability and water solubility of DOX and CPT were greatly improved, and the anticancer activities of chemotherap...

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Bibliographic Details
Main Authors: Mantao Chen, Chi Hu, Shengxiang Zhang, Dan Wu, Zhengwei Mao, Xiujue Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.867815/full