Optimization of cardiopulmonary bypass prime fluid to preserve microcirculatory perfusion during on-pump coronary artery bypass graft surgery: PRIME study protocol for a double-blind randomized trial

Optimization of cardiopulmonary bypass prime fluid to preserve microcirculatory perfusion during on-pump coronary artery bypass graft surgery: PRIME study protocol for a double-blind randomized trial

Abstract Background Acute microcirculatory perfusion disturbances and organ edema are important factors leading to organ dysfunction during cardiac surgery with cardiopulmonary bypass (CPB). Priming of the CPB system with crystalloid or colloid fluids, which inevitably leads to hemodilution, could c...

Full description

Bibliographic Details
Main Authors: Anne M. Beukers, Carolien S. E. Bulte, Ruben J. Bosch, Susanne Eberl, Charissa E. van den Brom, Stephan A. Loer, Alexander B. A. Vonk
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Trials
Subjects:
Cardiopulmonary bypass
Priming
Microcirculation
Colloid
Crystalloid
Albumin
Online Access:https://doi.org/10.1186/s13063-024-08053-5

Internet

https://doi.org/10.1186/s13063-024-08053-5

Similar Items