Global Profile of tRNA-Derived Small RNAs in Pathological Cardiac Hypertrophy Plasma and Identification of tRF-21-NB8PLML3E as a New Hypertrophy Marker

Global Profile of tRNA-Derived Small RNAs in Pathological Cardiac Hypertrophy Plasma and Identification of tRF-21-NB8PLML3E as a New Hypertrophy Marker

Background: It remains unclear whether transfer RNA-derived small RNAs (tsRNAs) play a role in pathological cardiac hypertrophy (PCH). We aimed to clarify the expression profile of tsRNAs and disclose their relationship with the clinical phenotype of PCH and the putative role. Methods: Small RNA seq...

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Bibliographic Details
Main Authors: Jingyi Xu, Buyun Qian, Feng Wang, Ying Huang, Xinxin Yan, Ping Li, Qian Zhang, Yuan Li, Kangyun Sun
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Diagnostics
Subjects:
transfer RNA-derived small RNAs
pathological cardiac hypertrophy
small RNA sequencing
biomarker
Online Access:https://www.mdpi.com/2075-4418/13/12/2065

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https://www.mdpi.com/2075-4418/13/12/2065

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