Active Components with Inhibitory Activities on IFN-γ/STAT1 and IL-6/STAT3 Signaling Pathways from Caulis Trachelospermi

Active Components with Inhibitory Activities on IFN-γ/STAT1 and IL-6/STAT3 Signaling Pathways from Caulis Trachelospermi

Initial investigation for new active herbal extract with inhibiting activity on JAK/STAT signaling pathway revealed that the extract of Caulis Trachelospermi, which was separated by 80% alcohol extraction and subsequent HP-20 macroporous resin column chromatography, was founded to strongly inhibit I...

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Bibliographic Details
Main Authors: Xiao-Ting Liu, Zhe-Xing Wang, Yu Yang, Lin Wang, Ruo-Feng Sun, Yi-Min Zhao, Neng-Jiang Yu
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Molecules
Subjects:
Caulis Trachelospermi
4-demethyltraxillaside
nortrachelogenin 4-O-β-d-glucopyranoside
JAK/STAT signaling pathway
Online Access:http://www.mdpi.com/1420-3049/19/8/11560

Internet

http://www.mdpi.com/1420-3049/19/8/11560

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