Sclareol exerts synergistic antidepressant effects with quercetin and caffeine, possibly suppressing GABAergic transmission in chicks

This study evaluated the effects of sclareol (SCL) with or without caffeine (CAF) and quercetin (QUR) using in-vivo and in-silico studies. For this, 5-day-old chicks weighing between 45 and 48 g were randomly divided into five groups and treated accordingly. The chicks were monitored to compare the...

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Bibliographic Details
Main Authors:	Hossam Kamli, Ahmad Shaikh, Mehedi Hasan Bappi, António Raposo, Md Faruque Ahmad, Fatema Akter Sonia, Md. Showkoth Akbor, Abdullah Al Shamsh Prottay, Sheila Alves Gonçalves, Isaac Moura Araújo, Henrique Douglas Melo Coutinho, Ehab Y. Elbendary, Linda Heejung Lho, Heesup Han, Muhammad Torequl Islam
Format:	Article
Language:	English
Published:	Elsevier 2023-12-01
Series:	Biomedicine & Pharmacotherapy
Subjects:	Depression Sleep duration Righting reflex Sclareol Quercetin GABAA receptor interaction
Online Access:	http://www.sciencedirect.com/science/article/pii/S0753332223015664

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http://www.sciencedirect.com/science/article/pii/S0753332223015664

Sclareol exerts synergistic antidepressant effects with quercetin and caffeine, possibly suppressing GABAergic transmission in chicks

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