Associations between rare microglia‐linked Alzheimer's disease risk variants and subcortical brain volumes in young individuals

Abstract Introduction Recent exome sequencing studies have identified three novel risk variants associated with Alzheimer's disease (AD). However, the mechanisms by which these variants confer risk are largely unknown. Methods In the present study, the impact of these rare coding variants (in A...

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Bibliographic Details
Main Author: Thomas M. Lancaster
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Online Access:https://doi.org/10.1016/j.dadm.2019.03.005